|
|
4-oxo-4-(pyridin-3-yl)butanal + H2O + NADP+ <=> 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H+
|
1.2.1.83
3-succinoylsemialdehyde-pyridine dehydrogenase
|
–
|
| |
BRENDA:
BR50147
KEGG:
R10105
MetaCyc:
RXN-13089
|
|
|
|
nicotine-Delta1''5''-iminium_ion + O2 + H2O <=> H+ + cotinine + H2O2
|
1.2.3
|
–
|
| |
MetaCyc:
RXN66-62
|
|
|
|
norcotinine <=> 4-oxo-4-(3-pyridyl)-butanamide
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-104
|
|
|
|
Nicotine + NADPH + O2 <=> nicotine-1''-N-oxide + NADP+ + H2O
|
1.14.13.101
senecionine N-oxygenase
1.14.13.8
flavin-containing monooxygenase
|
–
–
|
| |
BRENDA:
BS386007
MetaCyc:
RXN66-81
|
|
|
|
gamma-Hydroxy-3-pyridinebutanoate + acceptor <=> 4-oxo-4-(pyridin-3-yl)butanoate + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN66-141
|
|
|
|
(S)-nornicotine + H2O + acceptor <=> norcotinine + reduced_acceptor + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-103
|
|
|
|
2''-hydroxynicotine <=> 4-(methylamino)-1-(pyridin-3-yl)butan-1-one
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-147
|
|
|
|
Nicotine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2''-hydroxynicotine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
| |
MetaCyc:
RXN66-146
|
|
|
|
4-oxo-4-(3-pyridyl)-butanamide <=> 4-oxo-4-(pyridin-3-yl)butanoate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-105
|
|
|
|
Nicotine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> nicotine-Delta1''5''-iminium_ion + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
| |
MetaCyc:
RXN66-61
|
|
|
|
4-(methylamino)-1-(pyridin-3-yl)butan-1-one + O2 + H2O <=> 4-oxo-4-(pyridin-3-yl)butanal + methylamine + H2O2
|
1.4.3.24
pseudooxynicotine oxidase
|
–
|
| |
BRENDA:
BR50151
KEGG:
R10103
MetaCyc:
RXN-13088
|
|
|
|
gamma-Hydroxy-3-pyridinebutanoate <=> 4-(3-pyridyl)-3-butenoate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-142
|
|
|
|
UDP-glucuronate + Nicotine <=> nicotine-glucuronide + UDP
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN66-83
|
|
|
|
Nicotine + H2O + acceptor <=> reduced_acceptor + (S)-nornicotine + formaldehyde
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-101
|
|
|
|
4-(3-pyridyl)-butanoate + acceptor <=> 4-(3-pyridyl)-3-butenoate + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN66-144
|
|
|
|
4-(3-pyridyl)-butanoate <=> 3-pyridylacetate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-145
|
|
